The Saranac River system is one of the most popular water routes in the area. This drainage is made up of small lakes and ponds near Lake Clear, the three Saranac Lakes (Upper, Middle and Lower), Oseetah Lake and Lake Flower. The chain of lakes is a great place to paddle, offering open water, great views, and sandy beaches.

The Raquette River system offers some of the longest continuous paddling in the Park. There are several easy access points and the river is slow enough that it can be paddled in either direction. There are plenty of first come, first served campsites along the route.

The Saint Regis Canoe Area and surrounding waters offer a wide variety of route options making it a favorite of the paddling community. Interconnected with both short and long carries, this area is considered a pond hoppers paradise. Suitable for day and overnight trips and paddlers looking for a backcountry experience.

The Northern headwaters of the Saranac River drainage consist of a variety of wandering flows, small ponds, and large lakes. More suited to day paddling, but still offering multi-day paddling options, this area's diversity is great.

Little Tupper Lake and Lake Lila, located in the William C. Whitney Wilderness Area, offer some of the finest motorless paddling experiences in the Adirondacks. Little Tupper, the largest motor-free lake in the region, provides a serene setting for both day trips and overnight camping, with a challenging but rewarding traverse to Lake Lila for skilled adventurers. Lake Lila, accessible via a short carry, features scenic campsites, sandy beaches, and the opportunity to hike Mount Fredrica. For those seeking an even greater challenge, the Bog River Flow and Lows Lake offer extended backcountry routes, including the Oswegatchie-Lows Lake traverse and a rugged connection to Lake Lila via Bog Lake, requiring strong navigation skills and determination.